Profile of J. Woodland Hastings

Profile of David J. Mangelsdorf.

T wo decades ago, David Mangelsdorf did not expect his basic research findings to help launch an entire field of biology with farreaching implications for a raft of human diseases, including cancer, metabolic disorders, and parasitic infections. Mangelsdorf, a Howard Hughes Medical Institute investigator and a professor of pharmacology at the University of Texas Southwestern Medical Center at D...

Profile of Raymond J. Deshaies.

Protein homeostasis is crucial to the health of living cells, and dysregulated protein homeostasis can trigger diseases, including cancer. Biochemical cell biologist Raymond Deshaies has devoted his distinguished career to the analysis of protein homeostasis and the development of therapeutic approaches to counter diseases that result when homeostasis goes awry. Deshaies has served as a profess...

Profile of Scott J. Hultgren.

During her lifetime, an adult woman has a 50% chance of developing a urinary tract infection—one of the most common types of infections (1). Most urinary tract infections are caused by strains of the bacterium Escherichia coli, and, for the most part, are easily treated with antibiotics. However, many of these infections become chronic or recurrent because of increasing antibiotic resistance an...

Hastings Constitutional

Michael Hastings

Extraction of oil from Canadian tar sands is becoming increasingly contentious as it is claimed the process is one of the highest in terms of greenhouse gas emissions. But now, along with environmental campaigners, some shareholders in the companies that mine and fund tar sand oil are beginning to protest at the activity. British companies spearheading the drive to exploit the Canadian tar sand...